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Similarly Dilma et al tried
2024-06-14

Similarly Dilmaç et al. [16] tried to assess the diagnostic value of adenosine deaminase activity in sputum of patients with pulmonary tuberculosis, their aim was to determine and compare sputum ADA activity in pulmonary tuberculosis, lung cancer and chronic obstructive pulmonary disease (COPD) pati
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br Co http www apexbt com
2024-06-14

Conclusions This paper is the first meta-analysis about the association between SRD5A2 V89L polymorphism and hypospadias risk. The results of this meta-analysis have revealed that V89L polymorphism definitely increases the risk of hypospadias, and the C allele is a genetic risk factor for hypospa
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br Introduction In addition to ATP production an
2024-06-14

Introduction In addition to ATP production, an important role of mitochondria in the pancreatic beta cell is anaplerosis, which is the net synthesis of citric Compstatin receptor cycle intermediates that are exported to the cytosol where they are converted to numerous other metabolites that stim
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The canonical binding sites to which or contribute are highl
2024-06-14

The canonical aspartame products to which α2, α3, or α5 contribute are highly similar. Therefore, differences in ligand affinity will not be large even if a ligand makes optimal use of the small differences in the pockets. As a possible alternative approach to achieve separation of compound effects
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Our previous studies and others have identified that the
2024-06-13

Our previous studies and others have identified that the inhalational anesthetic isoflurane induces neuronal apoptosis via [Ca2+]i overload through the opening of synaptic voltage-dependent calcium channels (VDCCs) and the excessive Ca2+ release from the endoplasmic reticulum (Zhao et al., 2011; Zha
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There are several AP binding sites in the sequence of
2024-06-13

There are several AP-1 Olanzapine in the sequence of TIMP-1 promoter [18,19]. EBV could up-regulate TIMP-1 expression by binding to the AP-1 site in the TIMP-1 promoter [18]. IL-32, a newly multi-function cytokine, could activate AP-1, NF-κβ, p38MAPK signal pathways, and induce cytokine expressions,
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br Conflicts of interest br Contributors br Introduction Lip
2024-06-13

Conflicts of interest Contributors Introduction Lipid oxidation and enzymatic activities are some of the most significant problems in the food industry. These reactions lead to changes in chemical composition which in turn reduce the quality and shelf life of food products. Most of the anti
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br Future view and implications The selection and
2024-06-13

Future view and implications The selection and spread of multi(drug)-resistant microorganisms over the last decades has become a major and global public health concern [35]. Two growing threats originating from the fungal kingdom, i.e. Aspergillus fumigatus and Candida auris[36], [37], re-emphasi
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Introduction Plant pathogenic fungi are major
2024-06-13

Introduction Plant pathogenic fungi are major pathogens in agricultural diseases and the cause of large crop losses worldwide. There are many kinds of plant pathogenic fungi, with various modes of action. For example, Botrytis cinerea (B. cinerea) is the disease pathogen in the economically importa
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br Discussion Elevated blood BCAA levels are a common
2024-06-13

Discussion Elevated blood BCAA levels are a common feature of a developed pathophysiological state characterized by obesity and IR [4]. It has been suggested that this profile is part of a panel of biomarkers able to predict the onset of more severe complications like diabetes in humans [14]. In
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The finding that OCT is expressed in the nucleus accumbens
2024-06-13

The finding that OCT3 is expressed in the nucleus accumbens (Gasser et al., 2009) suggests that inhibition of this transporter may underlie previously described effects of glucocorticoids on extracellular DA concentrations and indicates that DA clearance in this region is not mediated exclusively by
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The difference in the mean values of serum ADA
2024-06-13

The difference in the mean values of serum ADA in sputum positive PTB and controls was found to be highly significant (P at the start of treatment and again after completion of IP in PTB patients. The fall in the levels of serum ADA was found to be statistically significant in both smear positive an
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Curcumin is the principal natural polyphenol curcuminoid of
2024-06-13

Curcumin is the principal natural polyphenol curcuminoid of turmeric (Curcuma longa) rhizome, a member of the ginger family (Zingiberaceae) [13]. Curcumin has a wide spectrum of therapeutic properties, and it has been shown to possess antioxidant, anti-inflammatory, anticancer, antiangiogenesis, che
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br Introduction ACK or Activated
2024-06-13

Introduction ACK1, or Activated Cdc42-Associated Kinase, located on chromosome 3q, is a ubiquitously expressed non-receptor tyrosine kinase cloned from a human BI6727 mg cDNA library (Manser et al., 1993). It was first identified to bind to activated Cdc42, a small Ras GTPase via its CRIB domain
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br lipoxygenase pathway in brain aging and alzheimer s
2024-06-12

5-lipoxygenase pathway in dilution factor calculator aging and alzheimer’s disease 5LO is found throughout the central nervous system, in both neuron and glia cells (Farias et al., 2007). However, its expression levels are highest in the cortex and hippocampus areas, two regions that are particul
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