• Park et al expanded their own model as hydrogen bonding

  2021-07-07

  

  Park et al. [34] expanded their own model as hydrogen- bonding lattice fluid EOS (NLF-HB) [35] for calculating the activity coefficients of aqueous amino citco solution. Further, Pazuki et al. [36] extended the perturbed hard chain theory which has been proposed by Beret and Prausnitz [37] for model

• br Study br Study meta

  2021-07-07

  

  Study 1 Study 2: meta-analyses Discussion Ten studies have examined the associations of 5-HTTLPR and COMT Val158Met with alexithymia. However, the findings were mixed. In this study, we found that neither the 5-HTTLPR nor COMT Val158Met is associated with alexithymia. The previous findings

• The mechanism underlying the increased PON levels

  2021-07-07

  

  The mechanism underlying the increased PON1 levels found in greenhouse workers may be accounted for by an increased protein ionomycin sale following pesticide interaction with different nuclear receptors as also occurs with other chemicals, such as polyphenols and statins [28]. A number of nuclear

• br EphB as a therapeutic target in cancer Eph receptors

  2021-07-07

  

  EphB4 as a therapeutic target in cancer Eph receptors and ephrins are promising new therapeutic targets in cancer. Various strategies have been employed to evaluate the interference of tumor-promoting effects or the enhancement of tumor suppressive effects. The inhibition of the Eph-ephrin system

• Introduction Obesity constitutes a global healthcare problem

  2021-07-07

  

  Introduction Obesity constitutes a global healthcare problem and has many adverse effects on the cardiovascular function [1,2]. Recently, the perivascular adipose tissue (PVAT) has emerged as a relevant fat depot for cardiovascular risk and as a potential trigger in vascular dysfunction. Indeed, PV

• br Acknowledgments The authors acknowledge funding from the

  2021-07-06

  

  Acknowledgments The authors acknowledge funding from the National Key Research and Development Program of China (2016YFA0502900) and the National Science Foundation of China (31570188). Compartment Size Regulation Regulation of compartment size is one of the most fundamental issues in biology

• Cancer patients may develop cachexia a deleterious

  2021-07-06

  

  Cancer patients may develop cachexia, a deleterious wasting syndrome that is associated with muscle atrophy and has an impact on the well-being of patients and on the response to the treatment. Indeed, cachexia is a devastating and often irreversible syndrome observed in up to 80% of cancer patients

• A key inciting event in atherosclerosis

  2021-07-06

  

  A key inciting event in atherosclerosis is the deposition of circulating low-density lipoprotein (LDL) in the subendothelial space of major arteries. In the subendothelium, native LDL is no longer protected by circulating antioxidants and is oxidatively modified to oxidized LDL (OxLDL) [5]. OxLDL is

• Dynasore We found that the postnatal absence of norepinephri

  2021-07-06

  

  We found that the postnatal absence of norepinephrine yields differing effects depending on noradrenergic receptor type and Dynasore region. The density of α1-AR, indicated by [3H]prazosin binding was similar between Dbh+/− and Dbh−/− mice except for a significant increase in hippocampus in Dbh−/−

• The second DDR binding partner identified here Shp which

  2021-07-06

  

  The second DDR1-binding partner identified here, Shp-2, which was not found in the two-hybrid screen but using a bioinformatics approach, is also a mediator of cell migration. Since Shp-2 has two SH2 domains, as well as phosphotyrosine phosphatase enzymatic activity and two C-terminal tyrosines targ

• The authentic PPase was purified from B subtilis as describe

  2021-07-06

  

  The authentic PPase was purified from B. subtilis as described previously [21], whereas the recombinant enzyme was purified to homogeneity from E. coli by a simplified procedure including only phenyl-Sepharose CL-4B column chromatography and DEAE-HPLC [21]. About 26 mg of pure enzyme was obtained fr

• DAPK is a kD Ca calmodulin

  2021-07-06

  

  DAPK is a 160-kD Ca2+/calmodulin (CaM)-regulated Ser/Thr kinase that mediates cell death. The activated forms of DAPK and DRP-1 are capable of inducing two distinct cytoplasmic events characteristic of programmed cell death, including membrane blebbing and the formation of autophagic vesicles (Inbal

• One of the most frequent gene alterations

  2021-07-06

  

  One of the most frequent gene alterations in MM is methylation of the p15 and p16 genes in the 5′ upstream region. P15 and p16 proteins are Pancuronium dibromide regulators involved in the inhibition of transition from G1 to S phase. Frequencies of p15 or p16 gene methylation up to 32% and 53%, res

• br Conflict of interest br Acknowledgments We

  2021-07-06

  

  Conflict of interest Acknowledgments We thank Jianru Zuo (Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China) for providing fbr11-1 seeds. We are grateful to Carol MacKintosh and the DSTT at the University of Dundee (UK) for anti-RD21 antibodies. This

• Prostaglandins PGs are lipid mediators that

  2021-07-06

  

  Prostaglandins (PGs) are lipid mediators that exhibit a variety of physiological properties by interacting specific G protein-coupled receptors (GPCRs) [10]. PGD2 is synthesized from PGH2 through two distinct PGD synthases; lipocalin-type PGD synthase (L-PGDS) and hematopoietic PGD synthase (H-PGDS)

14982 records 593/999 page Previous Next First page 上5页 591592593594595 下5页 Last page