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Era tal el recelo que hab a
2019-07-01
Era tal el recelo que había sobre el enriquecimiento de los ministros que en enero de 1622 se intentó investigar los orígenes de su riqueza. El mismo mes se publicó un decreto que estipulaba que todos los que habían tenido cargos Aminoallyl-dUTP molecular partir de 1592 debían inventariar sus propie
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br Quentin Eichbaum and colleagues describe how new medical
2019-07-01
Quentin Eichbaum and colleagues describe how new medical schools in Africa have developed curricula that include community and rural health components, long-term family attachments, and admission processes that are more equitable for disadvantaged students. All these worthwhile innovations have be
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Los sectores sociales movilizados espec ficamente las comuni
2019-07-01
Los sectores sociales movilizados, específicamente las comunidades afectadas por la industria extractiva y el movimiento indígena-amazónico, no lograron articular una plataforma conjunta que ampliara sus posibilidades de exigir un trato con Gana Perú en mayor igualdad de condiciones. Mientras aidese
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Rocilinostat weight La relaci n entre el narcotr fico y los
2019-07-01
La relación entre el narcotráfico y los grupos guerrilleros y los paramilitares se ha dado: “[…] no sólo como fuente de financiación sino como actor con intereses propios, ya que han aumentado significativamente las ‘familias’ que se dedican al tráfico de drogas, que a su vez están aumentando sus fo
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Adriana Kanzepolsky emple la met fora del dibujo para insinu
2019-07-01
Adriana Kanzepolsky empleó la metáfora del dibujo para insinuar la dimensión creativa de la selección editorial de los origenistas en su estudio Un dibujo del mundo. Extranjeros en Orígenes. Kanzepolsky describió cómo se modeló un esquema del mundo según los criterios de los colaboradores de una emp
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In this study we analyzed
2019-07-01
In this study, we analyzed the biological effects of two novel GATA2 mutations, which were identified in adult de novo AML patients. Materials and methods The diagnosis of AML was based on the morphology, histopathology, the expression of leukocyte differentiation Birinapant and/or the French–A
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While resistance to imatinib is rare in patients
2019-07-01
While resistance to imatinib is rare in patients treated in CML-CP, resistance does eventually develop in the majority of patients treated in the advanced phases. In a high proportion of patients who develop secondary resistance after initial responses, point mutations in the BCR-ABL kinase domain h
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br Hematopoietic cell transplantation HCT
2019-07-01
Hematopoietic cell transplantation HCT is generally recommended for AML patients with intermediate or high risk cytogenetics, when the aim of treatment is curative. However, elderly patients are seldom offered a transplant mainly due to concerns regarding toxicity, despite the fact that the main
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Fig shows an example of RNRVAS in
2019-06-29
Fig. 3 shows an example of RNRVAS in a dual-chamber pacemaker recipient with sinus node disease, with the pacemaker set in rate adaptive DDI-R mode pacing with an AV interval of 300ms and lower rate limit of 60ppm. The tracing shows sensor-driven DDIR pacing at 80bpm (V–V CP 31398 dihydrochloride le
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In the current era nearly all cases of hormone
2019-06-29
In the current era, nearly all cases of hormone-receptor positive breast cancer are treated with adjuvant endocrine therapy irrespective of staging, with preference for aromatase inhibitors over tamoxifen because of side effect profile, survival outcome and tumor recurrence rates [4,11]. In our stud
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Era tal el recelo que hab a sobre el
2019-06-29
Era tal el recelo que había sobre el enriquecimiento de los ministros que en enero de 1622 se intentó investigar los orígenes de su riqueza. El mismo mes se publicó un decreto que estipulaba que todos los que habían tenido cargos Pazopanib Hydrochloride partir de 1592 debían inventariar sus propieda
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IL IL is another potential
2019-06-29
IL-7: IL-7 is another potential inhibitor of OBL differentiation in MM that induces RANKL production by T lymphocytes [113] and mediates MM-induced OBL inhibition by down-regulating RUNX2 transcriptional activity [93]. IL-7 levels are increased in the marrow of MM patients and that IL-7 inhibited bo
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Heat shock facilitates the folding of various
2019-06-29
Heat shock facilitates the folding of various proteins as mediated by the HSP family and can stabilize mutant proteins. HS has been reported to facilitate maturation of WT-HERG as well as mutant HERG by activating the HSF family [15]. HSF-1, 2, and 4 were reported to be expressed in humans. HSF-1 is
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br Conflict of interest br Acknowledgments This
2019-06-29
Conflict of interest Acknowledgments This study was supported by the National Natural Science Foundation of China (Nos. 81273501 and 81470378). Introduction Sudden cardiac death (SCD) is a tragic event and the aftermath is devastating to the surviving family and community. SCD occurs in ne
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Autophagy can be generally divided
2019-06-29
Autophagy can be generally divided into non-selective bulk autophagy and selective autophagy. Non-selective autophagy breaks down proteins and organelles to provide the cell with nutrients in response to starvation. Selective autophagy removes damaged and excess organelles as well as protein Licofel
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